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bp0007rdr22 | The Ruminant Corpus Luteum | REDR2010

Regulation of corpus luteum development and maintenance: specific roles of angiogenesis and action of prostaglandin F

Miyamoto A , Shirasuna K , Shimizu T , Bollwein H , Schams D

Development of the corpus luteum (CL) in ruminants occurs in a rapid and time-dependent manner within 1 week after ovulation, with morphologic and biochemical changes in the cells of the theca interna and granulosa cells of the preovulatory follicle. These changes involve luteinisation of steroidogenic cells and angiogenesis to establish normal luteal function (progesterone secretion). The CL is composed of a large number of vascular endothelial cells, large and small steroido...